Specifications include, but are not limited to: The Department is seeking applications for the infrastructure planning and development for a variety ofLow Threshold Buprenorphine Induction (Low Threshold) programs. Buprenorphine has been shown tobe a safe and effective medication in multiple settings with extensive research on both unobservedinduction and physician-observed induction.2 Low threshold programs are designed to reduce barriers toMOUD, in this case buprenorphine specifically, by making minimal requirements of patients andoffering same day, immediate enrollment in buprenorphine treatment and wraparound casemanagement/recovery support services. After buprenorphine induction and when individuals are initially stabilized on the agent, they are transitioned to other programs where they receive maintenance buprenorphine. Low Threshold programs can occur in multiple contexts such as:•Hospital Emergency Department (ED)-Based Buprenorphine Induction Projects.•Mobile Health Unit Projects.•Pharmacy Buprenorphine Induction Projects.•Other Low Threshold Buprenorphine Projects