Specifications include, but are not limited to:. Western Washington University contemplates awarding a sole source purchase to Leica Microsystems for Stellaris 8 Laser scanning confocal microscope with a white light laser. The item is capable of confocal microscopy, super-resolution microscopy, fluorescence lifetime imaging, and fluorescence cross-correlation spectroscopy. The proposed instrument will transform research and teaching using modern tools of microscopy by enabling: increased spatial and temporal resolution beyond what is available at WWU analyses of protein-ligand interactions through Forster Resonance Energy Transfer (FRET) quantified by Fluorescence Lifetime imaging (FLIM) and analyses of protein dynamics by Fluorescence Correlation Spectroscopy (FCS) and Fluorescence Recovery after Photobleaching (FRAP) multiplexed imaging with eight overlapping fluorescent labels