Specifications include, but are not limited to: 2.3.1.A high-performance liquid chromatograph (LC) that includes and autosampler with a tray holder for 11mm autosampler vials and a well plate holder and having missing vial sensors. The autosampler need to handle injection volumes of 0.5 to 50 uL and have needle wash capabilities. Autosampler errors need to put LC pump in standby mode. 2.3.2.The LC pump needs to be binary or quaternary and have automatic compressibility compensation. The LC pump needs to handle pressure of up to 1300 Bar/18000psi and flow rates up to 5ml/min. The LC pump needs a purge valve and MS bypass capabilities installed. 2.3.3.Quote should include tray chiller, degasser, solvent reservoir tray, and column compartment with heating capabilities if not already include with system.