Specifications include, but are not limited to:. The NDOAG-CLD is in need of validating a multi-drug screening panel for the LC-ToF, a multi-drug quantitative panel for the LC-MS/MS and a THC panel for the LC-MS/MS to enhance the testing capabilities of the Toxicology Unit – Biological Section. Complete method validation services include onsite sample preparation, method development and validation. PinPoint testing provides validation services and is familiar with and follows ANSI/ASB Standard 036, First Edition 2019 Standard Practices for Method Validation in Forensic Toxicology. PinPoint Testing, LLC also provides the ToolBox kits which are necessary to complete a method validation and to prepare samples for a method validation. Validation experiments must include the following. Other experiments may need to be added as the need arises. Quantitation of THC, THC-OH, THC-COOH, and Cannabidiol in Whole Blood by LC/MS/MS Method Requirements Analytes; Limits of Detection and Quantitation; assay range. THC – 1 – 50 ng/mL THC-OH – 1 – 50 ng/mL THC-COOH – 5 – 100 ng/mL Cannabidiol – 1 – 50 ng/mL Standards and Controls The method must use matrix matched standards and controls. Positive and Negative Controls must be included in each batch.
