Awarded Component A Grantees will: 1. Focus regionally on supporting health systems to implement PHS Guideline system strategies 1 (screening systems), 2 (training, resources and feedback), and 3 (dedicated staffing plan), as outlined above. 2. Reach organizations across their catchment area that serve high priority population groups disproportionately affected by commercial tobacco, including patients with lowincome levels, low educational attainment, and/or those with serious mental illness. At a minimum, contractors will work with FQHCs, CHCs, behavioral health care organizations, and other organizations serving these priority groups throughout their catchment area to eliminate avoidable health inequities. 3. Emphasize the importance of organizational systems that address TUD among disproportionately affected population groups to achieve optimal health outcomes. 4. Engage health care stakeholders, educate health care professionals, and mobilize health care partners throughout the catchment area to strengthen systems and policies that facilitate quality and sustained tobacco dependence treatment. 5. Support health care organizations in building their capacity for integrated TUD treatment into their clinical workflows and protocols to ensure provision of equitable TUD treatment.