The City of Chicago (City), acting through the Chicago Department of Public Health (CDPH), seeks qualified organizations to provide Housing Opportunities for Persons with HIV/AIDS (HOPWA): Facilities-Based Housing Assistance. Funding for Facility-Based Housing Assistance may pay for community residential facilities – including community residences, single room occupancy (SRO) dwellings, short-term facilities, project-based rental units, and master leased units – serving low-income individuals with HIV and low-income families with at least one family member with HIV that are experiencing homelessness or are at risk of becoming homeless. Facility-Based Housing Assistance may include multiple apartments within the same building or building complex. The HOPWA Facilities-Based Housing Assistance Program is a partnership between the Chicago Department of Public Health and HOPWA Project Sponsors to provide a range of housing options to individuals with HIV and their families who are experiencing homelessness or unstable housing. This partnership and these efforts are critical in advancing CDPH’s vision where Chicagoans can achieve their optimal health and wellness. HOPWA operates on a housing-first model, meaning that individuals and families should be able to access housing without first needing to address any medical and/or behavioral challenges. Housing is a fundamental human right and the loss of housing must be an absolute last resort. HOPWA housing is intended to support individuals and families by providing them with stable housing from which they may access clinical and supportive services to achieve their desired health outcomes.