The County of San Diego Health and Human Services Agency (HHSA), through its Housing and Community Development Services (HCDS) division, is issuing this Notice of Funding Availability (NOFA) with the objective of supporting the construction, acquisition, and/or rehabilitation of affordable multi-family housing units. These units will serve households with extremely low (30% Area Median Income, or AMI), very low (50% AMI), and low-income (80% AMI) levels. Financing will be provided through HCDS-administered funding sources, subject to availability. Funding sources may include a combination of the following: Community Development Block Grant (CDBG) HOME Investment Partnerships Program (HOME) HOME Investment Partnerships Program American Rescue Plan (HOME-ARP) HOME Investment Partnerships Program Community Housing Development Organization (HOME-CHDO) Innovative Housing Trust Fund (IHTF) Permanent Local Housing Allocation (PLHA) Project-Based Vouchers (PBVs) Veterans Affairs Supportive Housing Project-Based Vouchers (VASH PBVs)