Specifications include, but are not limited to: The Department of Public Safety, Bureau of Emergency Medical Services (Department/EMS) is seeking MOUD Program Medical Direction Support as defined in this Request for Proposal (RFP) document. This document provides instructions for submitting proposals, the procedure, and criteria by which the awarded Bidder will be selected, and the contractual terms which will govern the relationship between the State of Maine (State) and the awarded Bidder. EMS is an integral partner in the State of Maine’s Opioid Response. EMS clinicians interact with thousands of Mainers every year who are experiencing an opioid overdose and require emergent intervention. Of those patient interactions, approximately 20-30% of patients who are resuscitated with naloxone hydrochloride refuse transport to the local emergency department. Maine EMS recognizes that transport to the local emergency department offers significant resources (i.e., pathways to recovery, referrals, and naloxone take-home kits) that are currently inaccessible to those individuals who ultimately refuse transport following an overdose. Therefore, Maine EMS is seeking to help bridge that gap between those resources and patients who refuse transport to the local emergency department. EMS clinicians will continue to strongly encourage all patients, including those resuscitated with naloxone, that transport to the hospital for a thorough evaluation and monitoring, as needed, is the most appropriate course of action; however, it is understood that not all patients will wish to be transported