Specifications include, but are not limited to: 2.1.Single-Quadrupole Mass Spectrometer - The mass spectrometer must demonstrate the following performance specifications at installation: 2.2.EI scan sensitivity S/N ≥ 2,000:1 1 pg OFN, m/z 272 2.3.EI SIM instrument detection limit IDL ≤ 10 fg 100 fg OFN, m/z 272 2.4.PCI MRM sensitivity1 S/N ≥ 1200:1 100 fg BZP, m/z 183 NCI SIM sensitivity1 S/N ≥ 1000:1 100 fg OFN, m/z 272 MS Mainframe The mass spectrometer must be capable of scanning at 20,000 amu/second (single scan) with 0.1 amu step resolution, to obtain classic, library-searchable mass spectra for narrow, fast-eluting peaks. The mass spectrometer must include a patented Advanced Scanning Speed Protocol (ASSP) function that retains sensitivity (prevents sensitivity loss) at high scan speeds of 10,000 amu/second or faster. The mass spectrometer must be capable of scan cycles up to 333 scans/second to obtain highly precise data for GCMS and comprehensive GC & CG Applications. The mass spectrometer must have a mass axis stability of ±0.1 amu over 48 hours (constant temperature). The mass spectrometer must be capable of acquiring 64 SIM channels per group, and 128 groups per method. The mass spectrometer must have a minimum dwell time of < 0.5 msec. The mass spectrometer must have a mass range of 1.5 to 1090 amu with unit mass resolution over the entire mass range. The mass spectrometer must have a variable resolution setting for Q1 ranging from 0.4 to 2.0 amu (FWHM definition). The mass spectrometer must have an electron multiplier detector, with low noise overdrive lens. The mass spectrometer must have a linear dynamic range of at least 8 x 106. The mass spectrometer must have an automatic interrupt system which provides protection against damage such as filament failure. The mass spectrometer must have an eco-friendly feature which reduces power consumption in standby mode by 35%. The system must be capable of entering the Ecology mode at the end of a batch, to reduce power and The GC must have an Ecology mode with Gas Saver function that considerably reduces carrier gas consumption after injection or during stand-by, without affecting performance and without requiring a second gas type (e.g. nitrogen). The mass spectrometer must be capable of combined synchronous acquisition modes, with simultaneous measurements in any combination, e.g., Scan/SIM. Quadrupole The mass spectrometer must have a quadrupole with pre-rods which can be removed for cleaning, to minimize maintenance. The mass spectrometer must have a quadrupole which remain in a fixed position and are not moved or opened during routine user maintenance, such as changing the column, cleaning the source, or replacing a filament, thus protecting the analyzer from contamination, dislocation, or misalignment. The mass spectrometer must have a quadrupole mass filter manufactured of solid metal rods and must not require constant heating as required by coated monolithic quartz (non-metal) quadrupoles.
