Specifications include, but are not limited to: To expand Knight campus capability in analyzing molecular interactions, the University is requesting a biolayer interferometry (BLI) machine for measuring binding affinities between proteins and other molecules such as proteins, peptides, and DNA/RNA, in a wide dynamic range. The University needs a system that is capable of measuring a wide range of affinities (pM to high µM range) and the ability to work both pure samples and samples in more complex media. Ability to control temperature or run with lower sample volumes are preferred. Machine should meet the following specifications: 2.1.1. Ability to work with 96 well plates and has at least 8 probes 2.1.2. Ability to go to control temperature (for example set at 25C or 37C) 2.1.3. Ability to measure affinities for protein-protein interactions of commonly used size at pM-high µM range 2.1.4. Ability for measuring affinities between proteins and other molecules (proteins of varying size and RNA) 2.1.5. Confirm that the BLI has several types of probes to bind proteins through different interactions (Nickel-NTA, streptavidin, etc.) 2.1.6. At a minimum two software licenses are required to be provided to the two labs purchasing the BLI 2.1.7. Must supply any instrument-specific tools required for routine equipment maintenance by University staff. 2.1.8. Minimum warranty period offered is 12 months from the date of commissioning. 2.1.9. Provide a comprehensive user manual including a list of common errors that one might encounter while using the equipment and possible troubleshooting. 2.1.10. Ability to ability to deliver prompt service assistance (at least within 24h online), repairs, and supply parts for the equipment in Eugene, Oregon, USA. 2.1.11. Workstation and monitor required to operate the printer. 2.1.12. Proposer must provide information regarding the cost and replacement of consumables associated with equipment use. (i.e. how long do probes last and what cost is associated with replacing them. If there is a lamp, what is the lifetime and how long does it last.)