Upstate is requesting proposals from qualified contractors (“Contractor” or “Bidder”) for the provision of a Clinical Decision Support System (“CDSS”) to support evidence-based clinical decision making and improve patient outcomes, which is described in this RFP, with intent of awarding a contract (“Contract” or “Resulting Agreement”) to the Bidder providing the best value (as defined in Section 2(C) to Upstate. The purpose of this Request for Proposal (“RFP”) is to review, select and implement a solution that will integrate seamlessly with existing workflows and align with our organization’s commitment to high quality patient centered care. The preferred solution should provide extensive, continuously updated and actionable medical content. The Clinical Decision Support System must deliver evidence based clinical guidelines, real time decision support at the point of care, comprehensive content across minimally 25 specialties, provide seamless integration with our Epic EMR, tools to ensure provider efficiency improving patient outcomes and tools for continuing education tracking such as CME credits. The proposed system should have seamless compatibility with our Epic EMR offering seamless integration. Allow for real time access from desktop, mobile deice and tablet devices. Usability offering efficient and intuitive search capabilities, actionable summaries, including algorithms, calculator and treatment plans.