Specifications include, but are not limited to: A comparison of voluntary versus involuntary treatment for substance use disorder on the outcomes of fatal and nonfatal opioid-related overdose, controlling for other factors. This work is informed by a health and racial equity frame and incorporates a population health approach that acknowledges the differential impact of substance use among historically marginalized communities and supports the mission of DPH to promote wellness and health equity for all people in the Commonwealth. By this Notice of Opportunity (NOO), the Department is accepting applications from parties interested in developing analytic plans and/or conducting analyses on behalf of the Department. The results of the analyses will be used by the Department, at its discretion, to assess health status or evaluate programmatic or policy initiatives. The results may also be included in reports issued by the Department. The data set to be analyzed, known as the Public Health Data Warehouse (PHD), was initially assembled to enable the Department to report on analyses of fatal and non-fatal opioid overdose as required by Chapter 55 of the Acts of 2015, as amended by Chapter 133 of the Acts of 2016 (Chapter 55). Details on the dataset and results of prior analyses are available on the Public Health Data Warehouse (PHD) webpage. The following populations have been identified as priority populations who have been disproportionately negatively impacted by substance use including: Individuals who identify as Black, Indigenous, and People of Color Individuals with disabilities and those who have access and functional needs Individuals experiencing homelessness or housing instability Individuals with mental illness and/or substance use disorders Individuals with a history of incarceration Individuals who are pregnant or post-partum Individuals living in rural settings Individuals who are veterans Individuals under the age of 22