1. TOXICITY The undiluted product must not be toxic to humans. Dispensing system concentrates must be tested as used. A product is considered toxic if any of the following criteria apply: Oral lethal dose 50 (LD50) ≤2000 mg/kg Inhalation lethal concentration (LC50) ≤ 20 mg/L* Toxicity shall be measured on the product as a whole. Alternatively, a mixture need not be tested if existing toxicity information demonstrates that each of the ingredients complies. The toxicity testing procedures should meet the requirements put forth by the Organization for Economic Cooperation and Development (OECD) Guidelines for Testing of Chemicals. These protocols include Acute Oral Toxicity Test (TG 401), Acute Inhalation Toxicity Test (TG 403), and Acute Dermal Toxicity Test (TG 402). 2. CARCINOGENS AND REPRODUCTIVE TOXINS The undiluted products must not contain any ingredients that are carcinogens or that are known to cause reproductive toxicity, as defined by the following agencies: Carcinogens: International Agency for Research on Cancer (IARC), National Toxicology Program (NTP), US Environmental Protection Agency, or the Occupational Health and Safety Administration (OSHA). Reproductive Toxicity: Those chemicals listed by the State of California under the Safe Drinking Water and Toxic Enforcement Act of 1986 (CA Code of Regulations, Title 22, Division 2, Subdiv. 1, Chapter 3, Sect. 1200, et seq.). Naturally occurring elements and chlorinated organics, which may be present as a result of chlorination of the water supply, are not considered ingredients if the concentrations are below the applicable maximum contaminant levels in the National Primary Drinking Water Standards found in 40 Code of Federal Regulations (CFR) Part 141. 3. SKIN AND EYE IRRITATION The undiluted product must not be corrosive to the skin or eyes. Dispensing-system concentrates must be tested as used. The undiluted cleaning product must not be corrosive to the skin. The undiluted cleaning product must also not be corrosive to the eye as tested using the bovine opacity and permeability test (BCOP) (Sina et al. 1995) after a 10- minute exposure. 4. SKIN SENSITIZATION The undiluted product must not be a skin sensitizer as tested by the OECD Guidelines for testing chemicals, Section 406. Dispensing system concentrates must be tested as used. JCPS shall also accept the results of other standard test methods, such as those described in Buehler (1994) or Magnusson and Kligman (1969), as proof that the product or its ingredients are not skin sensitizers. 5. COMBUSTIBILITY The undiluted product must not be combustible. The product or 99% of by volume of the product ingredients must have a flashpoint above 150° F, as tested using either the Cleveland Open Cup Tester (ASTM D92-97) or a closed cup method International Standards Organization (ISO) 13736 or ISO 2719. Alternatively the product must not sustain a flame when tested using ASTM D 4206.
