Specifications include, but are not limited to: The objective of this research is to develop a handbook for practitioners implementing traditional and advanced safety countermeasures to achieve reductions in wrong-way driving (WWD) incidents and crashes on roadways. The handbook should address areas of interest such as, but not limited to, the following: Assessing data and findings from previous WWD studies (including international sources) to quantify crash characteristics, identify countermeasures, assess their effectiveness, and identify gaps in the research; Retrofitting existing facilities and design of new facilities (e.g., interchanges, frontage roads, mainlines, ramps) to reduce the likelihood of WWD incidents and crashes; Evaluating (e.g., effectiveness, maintenance, performance, and life cycle cost) current and emerging technologies and practices to reduce WWD incidents and crashes; Identifying best practices, standard operating procedures, design criteria, justifications, performance measures, protocols, and traffic management center operations currently used to address WWD; Exploring relationships between WWD incidents and crashes and developing Crash Modification Factors or other evaluation factors for assessing countermeasures; Developing typical application sheets for WWD treatments and a sample investigation checklist for WWD incidents and crashes; and Developing methods of data collection to uniformly identify, investigate, and report WWD incidents and crashes.