Specifications include, but are not limited to: purchase a package of two flow cytometery instruments: a Becton Dickenson (BD) FACSymphony analyzer and a BD FACSARIA Fusion cell sorter with a biosafety hood. Such instruments are necessary for performing both clinical and basic science research, and are an important part of the infrastructure of an Academic Health Science Center. Flow cytometers are laboratory instruments that are used to analyze multiple physical and chemical characteristics of cells (or particles) that are suspended in fluid as they pass through a laser beam one cell at a time. The defined characteristics include cell size and granularity, amounts of specific markers on the cell surface and within the cell, or ongoing intracellular transient signaling events.