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cryo-TEM, DDD, and Automated Device


Location
Iowa
Publication Date
03/08/2019 06:33 AM EST
Closing Date
03/22/2019 01:00 PM EDT
Issuing Organization
Iowa State University
Solicitation Number
Description

Specifications include, but are not limited to: The cryo-TEM/DDD will be used to visualize biological macromolecular samples (e.g. protein and nucleic acids) at cryogenictemperatures for structural characterization. Data collected on this microscope will be used primarily for single-particleanalysis (SPA) to determine three-dimensional (3D) structures at intermediate to near-atomic resolution (3-10 ). Although theinstrument will be primarily used for SPA, suppliers are encouraged to offer configurations that could be used forcryo-tomography, electron crystallography, and micro electron diffraction (microED). In addition, when applicable, theinstrument will be used as a screening microscope to collect data to support application for time on high-end instrumentationat national facilities.

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