The Advancing Systems Change grant program offers funding toward projects that address root causes of health disparities, such as the promotion of social connectedness*, enhancement of inter-agency partnerships & collaboration, and incorporation of community-based decision-making in operations. A component of this work is intended to address needs identified in the 2024 Public Health Improvement Plan*, specifically Priority 2: Promoting Social Connectedness. These projects must directly serve populations who experience disadvantages due to inequities in policies, practices, social norms, and the distribution of resources. It is through dedication to these efforts that gradual system-level change can be accomplished.